Lactobacilli Cell Lerako

Selelekela: Lactobacilli Cell Wall

Lactobacilli ke libaktheria tsa lactic acid tse ajoang haholo libakeng tse fapaneng, joalo ka karolo ea mala ea liphoofolo le batho, limela, lijo tse lomositsoeng le lihlahisoa tsa lebese. Likokoana-hloko tsena li hlokomeloa haholo-holo ka bokhoni ba tsona ba ho hlahisa lactic acid e le sehlahisoa sa ho qetela sa metabolism ea bona. Ntle le tšobotsi ena, lactobacilli e na le sebopeho se ikhethileng se ba khethollang ho tsoa ho mofuta o mong oa baktheria: lerako la sele.

Lerako la sele ea baktheria ke lera le thata la ka ntle le fanang ka tšehetso le tšireletso ho lisele tsa baktheria. E boetse e phetha karolo ea bohlokoa tšebelisanong ea libaktheria le tikoloho ea tsona le likokoana-hloko tse ling. Tabeng ea lactobacilli, sebopeho le sebopeho sa lerako la lisele tsa bona esale e le taba ea boithuto ka lilemo tse mashome, ka lebaka la bohlokoa ba eona mafapheng a fapaneng joalo ka indasteri ea lijo, bophelo bo botle le biotechnology.

Sehloohong sena, re tla hlahloba ka botlalo sebopeho le litšoaneleho tsa lerako la sele ea lactobacilli, re totobalitse phello ea eona ts'ebetsong le ts'ebelisong ea likokoana-hloko tsena. Hape re tla sekaseka mekhoa e sebelisitsoeng ho li ithuta le ts'ebeliso e ka bang teng ea biotechnology e nkiloeng ho thetso ea lerako la lisele tsa lactobacillus.

Ka tlhahlobo ena, re tla tebisa tsebo ea rona ea lactobacilli le marako a lisele tsa eona, ho fana ka pono ea tekheniki le ea ho se nke lehlakore ho likokoana-hloko tsena tsa bohlokoa. Ho utloisisa sebopeho le mesebetsi ea lebota Sebopeho sa cellular sa lactobacilli se tla re lumella ho sebelisa bokhoni ba bona libakeng tse fapaneng joalo ka tlhahiso ea lijo tsa probiotic, kalafo ea mafu le boenjiniere ba liphatsa tsa lefutso.

1.- Selelekela ho Lactobacilli Cell Wall: Bohlokoa le litšobotsi tse akaretsang

Lactobacilli ke sehlopha sa libaktheria tsa lactic acid tse bapalang karolo ea bohlokoa ho belisoa ha lactic le tlhahiso ea lijo tse lomositsoeng. Libaktheria tsena li na le lerako le ikhethang la sele, le entsoeng haholo-holo peptidoglycan, e fanang ka botsitso le ho hanyetsa maemo a mabe. Bohlokoa ba lactobacilli ke bokhoni ba bona ba ho kopanya li-enzyme tse thusang tšilo ea lijo le ho monya limatlafatsi, hammoho le karolo ea tsona ea ho ba li-probiotics, ke hore, likokoana-hloko tse molemo bophelong.

Mabapi le litšobotsi tse akaretsang tsa lactobacilli, ke habohlokoa ho bolela hore ke libaktheria tsa Gram-positive, e leng se bolelang hore li boloka letheba la kristale violet leboteng la lisele tsa bona nakong ea tlhahlobo ea Gram stain. Ho feta moo, ke li-anaerobes tsa facultative, ke hore, li ka hola boteng le bosieong ba oksijene. Tšobotsi e 'ngoe ea bohlokoa ke bokhoni ba tsona ba ho belisa mefuta e mengata ea li-substrates, ho hlahisa lactic acid e le sehlahisoa sa ho qetela. Matla ana a ho bela a ba fa karolo ea bohlokoa tlhahisong ea lijo tsa lebese tse kang yokate le chisi.

Lerako la sele la lactobacilli le boetse le na le likarolo tse ling tse kang teichoic acid, lipoteichoic acid, le polysaccharides tse tlatsetsang ts'ebetsong ea tsona le bokhoni ba ho sebelisana le tikoloho. Likarolo tsena, hammoho le ho hanyetsa ha tsona ho li-bile acid le bokhoni ba tsona ba ho bokella pampitšana ea mala, li etsa hore lactobacilli e be sehlopha se amehang haholo sa libaktheria lebaleng la microbiology le bophelo bo botle ba batho. Ka bokhutšoanyane, lactobacilli ke likokoana-hloko tse nang le litšobotsi tse ikhethang le tsa bohlokoa haholo indastering ea lijo le bophelong ba batho.

2.- Sebopeho sa sebopeho sa lerako la sele ea Lactobacilli le tšusumetso ea eona mosebetsing oa likokoana-hloko

Lerako la sele ea Lactobacilli ke sebopeho se rarahaneng se bapalang karolo ea bohlokoa ts'ebetsong ea bona ea tlhaho. E entsoe haholo-holo ka li-polysaccharides, liprotheine le lipids tse etsang marang-rang a mararo a pota-potileng sele. Likarolo tsena li fana ka matla a sele le ho e sireletsa ho osmotic lysis, ntle le ho ikarabella bakeng sa sebopeho sa eona le botsitso ba sebopeho.

Har'a li-polysaccharides tse teng leboteng la sele ea Lactobacilli ke peptidoglycan le holim'a polysaccharides. Peptidoglycan ke sebopeho se thata se entsoeng ka ho pheta-pheta ha likarolo tsa N-acetylglucosamine le N-acetylmuramic acid, tse hokahaneng ke marokho a peptide. Karolo ena e fana ka ho tiea le ho hanyetsa lerako la sele. Ka lehlakoreng le leng, li-polysaccharides tse ka holimo li na le limolek'hule tse fetohang habonolo le tse sa tšoaneng tse fumanoang karolong e ka ntle. ea lerako la sele, le ho phetha karolo ea bohlokoa tšebelisanong ea Lactobacilli le tikoloho ea bona.

Liprotheine tse teng leboteng la sele ea Lactobacilli li fapane ebile lia sebetsa mesebetsi ea bohlokoa tšebetsong ea likokoana-hloko ea lisele. Liprotheine tsena li ka hokahana ka kopanelo le peptidoglycan, tsa etsa se tsejoang e le liprotheine tsa anchoring kapa li-cross-link. Ho boetse ho na le liprotheine tse tlamang tse sebelisanang ka kotloloho le likarolo tsa tikoloho ea kantle ho sele, joalo ka limolek'hule tsa tsoekere kapa liprotheine tsa matrix tsa extracellular. Litšebelisano tsena li bohlokoa bakeng sa ho khomarela Lactobacilli holim'a metsi, kolone ea lisele le likarabo tsa 'mele oa ho itšireletsa mafung.

3.- Mesebetsi ea bohlokoa ea lerako la sele ho Lactobacilli: tšireletso, botsitso le taolo

Mesebetsi ea bohlokoa ea lerako la sele ho Lactobacilli e bohlokoa haholo bakeng sa ho phela le ho sebetsa ka nepo. Tabeng ena, ho na le mesebetsi e meraro e ka sehloohong: tšireletso, botsitso le taolo.

Tšireletso: Lerako la sele la Lactobacilli le sebetsa joalo ka tšireletso khahlanong le lintho tse ka ntle, tse kang chefo ea baktheria le lik'hemik'hale tse teng tikolohong. E boetse e fana ka tšireletso e eketsehileng ka ho sebetsa e le mokhoa oa pele oa tšireletso khahlanong le tlhaselo ea pathogen, ho thibela ho khomarela le ho ba likolone holim'a mabala a moeti.

Botsitso: Lerako la sele le boetse le fana ka botsitso ba sebopeho ho Lactobacilli. Tšobotsi ena e lumella lisele tsa baktheria ho mamella maemo a mabe a tikoloho, a kang liphetoho tsa pH, mocheso o phahameng le liphetoho tsa osmotic. Lerako la sele le boetse le tiisa botšepehi ba lisele le ho thibela baktheria lysis le apoptosis.

Taolo: Lerako la sele le bapala karolo ea bohlokoa ho laoleng lits'ebetso tsa 'mele tsa Lactobacilli. Likarolo tse fapaneng tsa lerako, joalo ka li-polysaccharides le li-peptide, li ka fetola ho khomarela, kolone, le tšebelisano le moamoheli. Ho feta moo, ho satalla le ho hlophisoa ha lerako la lisele ho ka susumetsa bokhoni ba ho susumetsa likarabo tsa 'mele oa ho itšireletsa mafung, tse bohlokoa haholo bakeng sa bophelo bo botle ba mala le karabelo ea 'mele ea ho itšireletsa mafung.

4.- Thuto ea ho fetoha ha sebopeho le sebopeho sa lerako la sele ea Lactobacilli

Lactobacilli ke likokoana-hloko tse ithutoang haholo ka lebaka la bohlokoa ba tsona likarolong tse fapaneng tse kang indasteri ea lijo le bophelo bo botle ba batho. Karolong ena, re tla sebetsana le thuto ea ho fetoha ha sebopeho le sebopeho sa lerako la lisele tsa likokoana-hloko tsena.

Lerako la sele la lactobacilli ke sebopeho sa bohlokoa se fanang ka tšireletso le ho tiea ho lisele. E entsoe haholo-holo ka peptidoglycan, polymer e etsang meshwork ea mahlakore a mararo ho potoloha sele. Leha ho le joalo, phapang e kholo sebopehong sa peptidoglycan ena e bonoa lipakeng tsa mefuta e fapaneng le mefuta ea lactobacilli.

Ntle le peptidoglycan, lerako la sele la lactobacilli le ka ba le likarolo tse ling tse kang teichoic acid, polysaccharides le liprotheine. Boteng le bongata ba likarolo tsena li ka fapana haholo har'a mefuta e fapaneng ea lactobacillus, e tlatsetsang ho se tšoane ha tsona ho latela litšobotsi tsa phenotypic le ts'ebetso. Liphapang tsena tsa sebopeho sa lerako la lisele le sebopeho li ka susumetsa ho hanyetsa maemo a mabe a tikoloho, ho khomarela bokaholimo, le tšebelisano. le sistimi immunological, hara mesebetsi e meng ya baeloji.

5.- Tšebelisano ea Lactobacilli Cell Wall le tikoloho le likokoana-hloko tse ling

Tšebelisano ea lactobacilli le tikoloho le likokoana-hloko tse ling ke ntlha ea bohlokoa e lokelang ho nahanoa thutong ea likokoana-hloko tsena. Lactobacilli ke libaktheria tse khetholloang ka bokhoni ba tsona ba ho belisa tsoekere le ho e fetola lactic acid.

Lerako la sele ea lactobacilli le phetha karolo ea bohlokoa tšebelisanong ea bona le tikoloho le li-microorganisms tse ling. Sebopeho sena se na le litšobotsi tse 'maloa tse e lumellang ho sireletsa libaktheria ho tloha maemong a mabe le ho nolofatsa ho khomarela ha tsona holimo. Tse ling tsa litšebelisano tse hlokomelehang tsa lactobacilli ke:

• Tlhōlisano le likokoana-hloko tse ling: Lactobacilli e ka hlōlisana le likokoana-hloko tse ling bakeng sa limatlafatsi le sebaka se tikolohong. Bokhoni ba bona ba ho hlahisa lactic acid le lintho tse ling tse thibelang likokoana-hloko bo ba fa monyetla oa tlhōlisano.
• Tšebelisano le likokoana-hloko tse ling: Maemong a mang, lactobacilli e ka theha likamano le likokoana-hloko tse ling, joalo ka mefuta e itseng ea bifidobacteria. Tšebelisano ena e ka ba molemo bakeng sa likokoana-hloko ka bobeli, kaha li ka tlatsana le mesebetsi ea metabolism.
• Tšebelisano ea Host: Lactobacilli e ka boela ea sebelisana le moeti tabeng ea li-probiotics. Likokoana-hloko tsena li ka bokella tšilo ea lijo ea motho 'me tsa ba le litlamorao tse ntle tsa bophelo bo botle, joalo ka ho ntlafatsa ts'ebetso ea mala le ho matlafatsa sesole sa' mele.

Qetellong, tšebelisano ea lactobacilli le tikoloho le likokoana-hloko tse ling ke sehlooho se bohlokoa haholo ho microbiology. Libaktheria tsena li sebelisa lerako la lisele tsa tsona le maano a mang ho qothisana lehlokoa le likokoana-hloko tse ling, ho theha likamano le ho thusa moamoheli. Boithuto ba litšebelisano tsena bo ka kenya letsoho ho nts'etsopele ea li-probiotics le lits'ebetso tse ling biotechnology.

6.- Melemo e ka bang teng bakeng sa bophelo bo botle ba motho e amanang le ho ba teng ha Cell Wall Lactobacilli

Ho ba teng ha cell wall lactobacilli 'meleng oa motho ho fana ka melemo e mengata ea bophelo bo botle. Melemo ena e hlahisoa ke thepa e ikhethang ea lactobacilli, e ka kenyang letsoho ho ntlafatseng sesole sa 'mele le ho khothaletsa ho leka-lekana ho leka-lekaneng ka har'a gut microbiota.

Tse ling tsa melemo ea bophelo bo botle e amanang le Lactobacilli Cell Wall ke:

• Ho matlafatsa sesole sa 'mele: Lactobacilli e na le matla a ho susumetsa tlhahiso ea lisele tse ling tsa 'mele tsa ho itšireletsa mafung, tse ka thusang ho matlafatsa sesole sa' mele ho arabela tšoaetsong le mafung.
• Bophelo bo botle ba mala a ntlafetseng: Lactobacilli e ka thusa ho boloka botsitso bo botle ka har'a gut microbiota ka ho thibela kholo ea libaktheria tse kotsi. Sena se ka kenya letsoho ntlafatsong ea tšilo ea lijo le ho monya limatlafatsi, le ho fokotsa matšoao a amanang le mathata a mala a kang letšollo.
• Ho khothaletsa bophelo bo botle ba botšehali: Mefuta e meng ea lactobacilli e ka 'na ea e-ba teng ka tlhaho ka botšehaling' me ea phetha karolo ea bohlokoa ho thibela tšoaetso ea botšehali, e kang e bakoang ke baktheria ea Candida.

Tsena ke tse ling tsa melemo ea bophelo bo botle e amanang le Lactobacilli Cell Wall. Leha ho le joalo, ke habohlokoa ho hlokomela hore lipatlisiso lefapheng lena li ntse li tsoela pele 'me ho hlokahala lithuto tse ngata ho netefatsa le ho utloisisa ka botlalo liphello tse molemo tsa likokoana-hloko tsena' meleng oa motho.

7.- Liphello bakeng sa indasteri ea lijo le probiotic: lits'ebetso le ntlafatso ea lerako la lisele tsa Lactobacilli

Lipatlisiso mabapi le litlamorao tsa indasteri ea lijo le li-probiotic li senotse lits'ebetso le menyetla e fapaneng ea ho ntlafatsa lerako la lisele tsa Lactobacilli. Likokoana-hloko tsena, li teng ka tlhaho Lijong tse joalo ka yogurt, li bonts'itsoe li na le litlamorao ho bophelo bo botle ba motho, li ntlafatsa tšilo ea lijo le ho matlafatsa sesole sa 'mele. ⁤Ka ho fetola lerako la lisele tsa bona, hoa khoneha ho ntlafatsa thepa ea bona ea probiotic le ho atolosa tšebeliso ea bona lihlahisoa tsa lijo⁤ le lisebelisoa tsa lijo.

E 'ngoe ea ts'ebeliso e hlokomelehang ea Lactobacillus cell wall optimization ke tlhahiso ea lijo tse sebetsang hantle. Lijo tsena li na le metsoako e fanang ka melemo e meng ea bophelo bo botle ho feta boleng ba tsona ba phepo e nepahetseng. Ka ho ntlafatsa bokhoni ba Lactobacilli ho khomarela lerako la mala le ho pholoha tselaneng ea tšilo ea lijo, lijo tse sebetsang tse nang le litaba tse phahameng tsa li-probiotics tse sebetsang li ka fumanoa. Sena se bohlokoa haholo ho batho ba nang le mathata a mala kapa ba lakatsang ho matlafatsa mala a bona a microbiota.

Sebaka se seng moo litlamorao tsa ntlafatso ea lerako la lisele tsa Lactobacillus li ntseng li hlahlojoa ke indastering ea probiotic. Liphuputso tsa morao-rao li bontšitse hore phetoho ea lerako la lisele e ka eketsa botsitso le ho sebetsa ha likokoana-hloko tsena nakong ea tlhahiso le polokelo. Ho feta moo, ho 'nile ha hlokomeloa hore ho ntlafatsa lerako la lisele ho ka ntlafatsa ho hanyetsa maemo a mabe, a kang acidity ea mala, e leng ea bohlokoa ho netefatsa hore li-probiotics li sebetsa hantle. Tsoelo-pele ena ea theknoloji ea Lactobacillus e bula menyetla e mecha bakeng sa nts'etsopele ea lihlahisoa tsa probiotic. boleng bo phahameng ⁤le⁢ katleho.

8.- Mekhoa ea ho etsa lipatlisiso le mekhoa ea ho hlahloba thuto ea Cell Wall Lactobacilli

Lerako la sele ea Lactobacilli ke karolo ea bohlokoa ea ho utloisisa sebopeho le tšebetso ea tsona. Ho sebelisoa mekhoa le mekhoa e fapaneng ho etsa lipatlisiso le ho sekaseka tšobotsi ena, e re lumellang ho fumana leseli le felletseng mabapi le sebopeho sa bona le thepa ea bona. Ka tlase, re hlahisa tse ling tsa mekhoa e sebelisoang haholo thutong ea lerako la lisele tsa Lactobacilli:

1. Phetiso ea electron microscopy (TEM): Mokhoa ona o lumella ho fumana litšoantšo tse phahameng tsa lerako la sele ea Lactobacilli boemong ba microscopic. Ka TEM, likarolo tse fapaneng tsa lerako la sele li ka bonoa, joalo ka li-teichoic acid, polysaccharides le liprotheine. Ho feta moo, mokhoa ona o lumella ho khetholla liphetoho sebopeho sa lerako la sele ho latela maemo a tikoloho kapa liphekolo tse itseng.

2. Thin layer chromatography: Thin-layer chromatography ke mokhoa o sebelisoang ho arola le ho sekaseka likarolo tse fapaneng tsa lerako la lisele tsa Lactobacilli. U sebelisa mokhoa ona, hoa khoneha ho khetholla lipids, polysaccharides le metabolites tse ling tse teng leboteng la sele. Ntle le moo, chromatography ea lera le tšesaane e etsa hore ho khonehe ho tseba sebopeho sa lerako la sele le ho utloisisa liphetoho tse ka bang teng ho latela maemo a fapaneng a setso.

3. Fourier transform infrared spectroscopy (FTIR): FTIR ke mokhoa o lumellang tlhahlobo ea sebopeho sa lik'hemik'hale tsa likarolo tse teng leboteng la sele ea Lactobacilli. Ho sebelisoa mokhoa ona, ho fumanoa li-spectra tse fanang ka tlhahisoleseding mabapi le lihlopha tse sebetsang tse teng likarolong tsa lerako la sele, tse kang li-peptide bond, lihlopha tsa carboxyl le lihlopha tsa hydroxyl. FTIR ke mokhoa o sebetsang oa ho tseba liphetoho tsa sebopeho sa lik'hemik'hale leboteng la sele le ho bapisa mefuta e fapaneng ea Lactobacilli ho latela sebopeho sa eona.

9.- Mathata le litebello tsa nako e tlang liphuputsong tsa Lactobacilli Cell Wall

10.- Litlhahiso tsa tšebeliso e nepahetseng ea Lactobacilli ⁤Cell Wall ⁤ indastering

Litlhahiso tsa tšebeliso e nepahetseng ea Cell Wall Lactobacilli indastering

Ts'ebeliso ea cell wall lactobacilli indastering ea lijo e ntse e ata haholo ka lebaka la melemo ea bophelo bo botle le boleng ba lihlahisoa tse fanoang ke likokoana-hloko tsena. Leha ho le joalo, ho netefatsa ts'ebeliso e nepahetseng le ho eketsa litlamorao tsa bona, likhothaletso tse ling li tlameha ho lateloa:

1. Khetho e Lekaneng ea Lactobacilli Cell Wall: Ho bohlokoa ho khetha mefuta e ikhethileng ea Lactobacilli Cell Wall e tsamaellanang le lihlahisoa le lits'ebetso tsa indasteri eo ho buuoang ka eona. Mofuta o mong le o mong o na le litšobotsi le melemo e itseng, ka hona, ho bohlokoa ho batla likeletso le ho khetha e lumellanang hantle le litlhoko tse ikhethang tsa k'hamphani.

2. Taolo e felletseng ea maemo a ho belisoa: Ho netefatsa katleho ea Lactobacilli Cell Wall kopo, ho bohlokoa ho boloka taolo e matla ea maemo a ho belisoa. Sena se kenyelletsa ho lekola mocheso ka linako tsohle, pH, khatello ea limatlafatsi le nako ea ho belisoa. Tikoloho e loketseng e bohlokoa ho khothaletsa ts'ebetso le katiso ea Lactobacilli Cell Wall, hammoho le ts'ebetso ea bona e phahameng.

3. Ho beha leihlo le ho sekaseka liphetho: Ho eletsoa ho tsoela pele ho beha leihlo le ho sekaseka liphetho tse fumanoeng kamora ho sebelisoa ha Lactobacilli Cell Wall. Sena se kenyelletsa ho beha leihlo ntlafatso ea boleng ba sehlahisoa, ho lekola phello ea eona bophelong ba lishelefo le polokeho ea lijo, hammoho le ho fana ka maikutlo ho bareki ho lekola kamohelo ea bona. Lintlha tse bokelletsoeng li tla lumella ts'ebeliso ea likokoana-hloko tsena ho lokisoa le ho ntlafatsoa. ka katleho le ho sebetsa nakong e tlang.

11.- Tlhahlobo ea phello ea lerako la lisele tsa Lactobacillus bophelong ba liphoofolo le tšebeliso ea eona e ka bang teng ho bongaka ba liphoofolo.

Lerako la sele la Lactobacilli, mofuta oa libaktheria tse molemo, le tsositse thahasello e kholo sechabeng sa saense ka lebaka la phello e ka bang teng bophelong ba liphoofolo. Liphuputso tse ngata li entsoe ho lekola litlamorao tsa lerako la sele ena mefuteng e fapaneng ea liphoofolo, joalo ka likhomo, likolobe le likhoho. Liphetho ho fihlela joale li fana ka maikutlo a hore tsamaiso ea Lactobacilli le lerako la lisele tsa tsona li ka khothaletsa melemo e mengata ea bophelo bo botle bakeng sa liphoofolo, hammoho le ho fana ka menyetla ea kopo ea bona ea bongaka ba liphoofolo.

Tse ling tsa liphuputso tse hlahelletseng ho tsoa litlhahlobong tsena li kenyelletsa:

• Mosebetsi o ntlafetseng oa mala: Lerako la sele ea Lactobacilli le bontšitsoe hore le na le thepa ea prebiotic mme le ka susumetsa kholo ea libaktheria tse molemo ka har'a pampiri ea mala ea liphoofolo. Sena, ka lehlakoreng le leng, se ka ntlafatsa tšilo ea lijo le ho monya limatlafatsi, hammoho le ho matlafatsa ts'ebetso ea mokoallo oa mala.
• Ho tsosoa ha sesole sa 'mele: Ho hlokometsoe hore tsamaiso ea Lactobacilli le lerako la lisele tsa tsona li ka eketsa karabelo ea 'mele ea ho itšireletsa mafung ho liphoofolo, kahoo ea matlafatsa tsamaiso ea tsona ea ho itšireletsa khahlanong le mafu a sa tšoaneng le likokoana-hloko.
• Ho fokotsa khatello ea maikutlo le ho ruruha: Ho 'nile ha boleloa hore lerako la sele ea Lactobacilli le ka ba le liphello tse ntle ho fokotsa khatello ea kelello le ho ruruha ho liphoofolo ka ho laola karabelo ea' mele ea ho itšireletsa mafung. ea tsamaiso ea methapo le ho leka-lekana ha li-cytokine tsa proinflammatory.

Liphetho tsena tse ts'episang li bula maikutlo a macha lefapheng la bongaka ba liphoofolo, moo ho kenyelletsoa ha Lactobacilli le lerako la lisele tsa bona lijong kapa joalo ka litlatsetso tsa phepo e ka ba maano a sebetsang a ho ntlafatsa bophelo bo botle le boiketlo ba liphoofolo. Leha ho le joalo, ho bohlokoa ho totobatsa hore lipatlisiso tse ling li ntse li hlokahala ho utloisisa ka botlalo mekhoa ea ts'ebetso le ho fumana litekanyetso tse nepahetseng bakeng sa mofuta o mong le o mong oa phoofolo.

12.- Mekhoa e ka khonehang ea ho fetola lerako la sele ea Lactobacilli ho ntlafatsa ts'ebetso ea bona ea ts'ebetso

E 'ngoe ea mekhoa e tšepisang ea ho ntlafatsa ts'ebetso ea Lactobacilli ke phetoho ea lerako la lisele tsa bona. Ka ho etsa sena, sepheo ke ho eketsa bokhoni ba bona ba ho khomarela lisele tsa epithelial tsa mala, ho ntlafatsa botsitso ba bona nakong ea ts'ebetso ea tšilo ea lijo le ho ntlafatsa bokhoni ba bona ba ho lokolla metsoako ea bioactive e molemo bakeng sa bophelo bo botle.

Ho na le mekhoa e fapaneng ea ho etsa liphetoho tsena, tseo har'a tsona li hlahelletseng:

• Phetoho ea sebopeho: E kenyelletsa ho fetola karolo ea likarolo tse teng leboteng la sele ea Lactobacilli. Ka mohlala, palo ea li-teichoic acid le li-exopolysaccharides li ka eketseha, e leng limolek'hule tse tsejoang ho khothalletsa ho khomarela lisele tsa mala le karabelo ea 'mele ea ho itšireletsa mafung.
• Ho kenyelletsoa ha limolek'hule tsa bioactive: E kenyelletsa ho kenya lintho tse sebetsang ka har'a lebota la sele ea Lactobacilli ho ntlafatsa thepa ea bona ea ts'ebetso. E ka finyelloa ka mekhoa ea boenjiniere ba liphatsa tsa lefutso, joalo ka ho kenyelletsa liphatsa tsa lefutso tse nang le khoutu bakeng sa tlhahiso ea metsoako ea bophelo bo botle, joalo ka li-short-chain fatty acids.
• Lebota la lisele: E na le ho koahela lerako la sele ea Lactobacilli ka lintho tse sireletsang kapa ho li kenya ka har'a matrices a polymeric. Sena se thusa ho ntlafatsa ho hanyetsa ha bona ho li-acids tsa ka mpeng le li-enzyme tsa tšilo ea lijo, le ho thusa ho lokolloa ha bona ka maleng.

Mekhoa ena ea ho fetola lebota la lisele tsa Lactobacillus e emela sebaka se ts'episang sa lipatlisiso ho biotechnology ea lijo le microbiology e sebelisitsoeng. Kopo ea bona e ka lumella ho qaptjoa ha mefuta ea Lactobacillus e nang le thepa e ntlafetseng, e ka sebelisoang e le li-probiotics tse atlehang haholoanyane ho khothalletsa bophelo bo botle ba mala le ho thibela maloetse.

13.- Lithuto tse bapisoang tsa lerako la sele ea Lactobacilli ka mefuta le mefuta e fapaneng

14.- Liqeto le maikutlo a ho qetela ka Cell Wall Lactobacilli: tsela e lebisang tsebong e kholo le lits'ebetso.

Qetellong, boithuto ba lactobacilli cell wall bo senotse leseli la bohlokoa bakeng sa kutloisiso e betere ea biology ea bona le ts'ebeliso e ka bang teng. Ka mekhoa ea tatellano ea liphatsa tsa lefutso, re khonne ho khetholla liphatsa tsa lefutso tse ncha tse amehang ho kopanngoeng ha lerako la lisele tsa likokoana-hloko tsena, tse re atametsang haufi le pono e feletseng ea sebopeho le mosebetsi oa tsona. Ho phaella moo, ho bontšitsoe hore lerako la sele ea lactobacilli le na le thepa ea immunomodulatory le bokhoni ba ho sebelisana le mala a mala, a ka bang le liphello ho thibela le ho phekola mafu a mala.

Ka pono, bokamoso ba lipatlisiso mabapi le lerako la cell lactobacilli bo shebahala bo ts'episa. Tsoelopele ea theknoloji e lebelletsoe ho lumella boithuto bo boholoanyane ba litšebelisano lipakeng tsa likokoana-hloko tsena le tikoloho ea tsona, hammoho le ho khetholla metsoako e mecha ea bioactive le mekhoa ea ts'ebetso. Liphuputso tsena ha lia ka tsa atolosa tsebo ea rona ea lactobacilli ea lisele, empa hape li fana ka mekhoa e mecha ea phekolo bakeng sa phekolo ea mafu a sa tšoaneng a amanang le tsamaiso ea 'mele ea ho itšireletsa mafung le ea' mele ea ho itšireletsa mafung.

Ka bokhutšoanyane, boithuto ba cell wall lactobacilli bo re lebisitse ho sibolla likarolo tse khahlang tsa biology ea bona le ts'ebeliso e ka bang teng. Ka tsoelo-pele e 'ngoe le e 'ngoe kutloisisong ea rona ea likokoana-hloko tsena, menyetla e mecha ea tšebeliso ea tsona indastering ea lijo, meriana le tlhokomelo ea bophelo lia buleha. Ha re ntse re tsoela pele ho hlahloba lefats'e la bona la microscopic, re na le bonnete ba hore re tla fumana melemo le ts'ebeliso e eketsehileng ea cell wall lactobacilli, e leng se etsang hore sebaka sena sa lipatlisiso e be tsela ea ho fumana tsebo le menyetla e mengata.

Lipotso le Likarabo

P: Lactobacilli ⁢Cell Wall ke eng?
A: Cell Wall Lactobacilli ke libaktheria tsa lactic acid tse khetholloang ka ho ba le lera la sele le nang le li-polysaccharides tse ngata, tse li fang khanyetso e kholo le bokhoni ba ho phela ka har'a pampiri ea mala.

P: Bohlokoa ba Lactobacilli Cell Wall ke bofe?
A: Lactobacilli Cell Wall e na le melemo e mengata ea bophelo bo botle, kaha e matlafatsa sesole sa 'mele, e ntlafatsa tšilo ea lijo, e laola limela tsa mala, le ho thibela mafu a ka mpeng. Li boetse li bontšitsoe hore li na le liphello tse ntle ho fokotsa k'holeseterole le ho thibela mefuta e itseng ea kankere.

P: Lactobacilli Cell Wall e sebetsa joang 'meleng?
A: Cell Wall Lactobacilli e sebetsa haholo-holo ka mpeng ea mala, moo ba khomarelang mucosa ea mala le ho hlōlisana le likokoana-hloko tsa pathogenic, ho thibela ho ata ha bona le ho khomarela lisele tsa mala. Ho phaella moo, li susumetsa tlhahiso ea lactic acid le lintho tse ling tse thibelang likokoana-hloko tse thibelang ho hōla ha libaktheria tse kotsi le li-fungus.

P: Mehloli ea Lactobacilli Cell Wall ke efe?
K: Cell wall lactobacilli e fumanoa lijong tse lomositsoeng tse kang yogurt, chisi, sauerkraut le miso. Li ka boela tsa fumanoa ka lisebelisoa tsa lijo le lihlahisoa tse khethehileng tsa probiotic.

P: Na ho na le li-contraindication kapa litla-morao tse amanang le ho ja Lactobacilli Cell Wall?
A: Ka kakaretso, Lactobacillus Cell Wall e bolokehile ebile e mamelloa hantle. Leha ho le joalo, maemong a sa tloaelehang haholo, batho ba bang ba ka 'na ba e-ba le matšoao a bonolo a mala a kang flatulence, bloating, kapa letšollo. Tlhokomeliso e boetse e eletsoa ho batho ba nang le tsamaiso ea 'mele ea ho itšireletsa mafung e fokolang kapa bakuli ba sepetlele, kaha ho ka ba le kotsi e fokolang ea tšoaetso.

P: Tekanyetso e khothaletsoang ea Lactobacilli Cell Wall ke efe?
A: Tekanyo e khothaletsoang ea Lactobacilli Cell Wall e ka fapana ho latela sehlahisoa le boemo ba motho ka mong. Ho khothalletsoa ho latela litaelo tsa moetsi kapa ho buisana le setsebi sa bophelo bo botle ho fumana tekanyo e nepahetseng tabeng e 'ngoe le e 'ngoe e khethehileng.

P: Ho nka nako e kae ho hlokomela melemo ea Lactobacilli Cell Wall?
A: Melemo ea Lactobacilli Cell Wall e ka fapana. ea motho ho e mong mme⁢ ho ipapisitse le ⁢ lintlha tse 'maloa, joalo ka lethal dose, ho sebelisoa khafetsa le bophelo bo botle ba motho ka mong.

P: Na ho bolokehile ho sebelisa Lactobacillus Cell Wall nakong ea bokhachane kapa ho anyesa?
A: Ka kakaretso, Lactobacilli Cell Wall e nkoa e sireletsehile nakong ea bokhachane le ho anyesa. Leha ho le joalo, ho kgothaletswa ho buisana le ngaka pele o qala ts'ebeliso ea eona, haholo-holo maemong a boimana bo kotsi kapa boteng ba maemo a itseng a bongaka.

P: Na Lactobacilli Cell Wall e ka kopanngoa le meriana e meng?
A: Maemong a mangata, Lactobacillus Cell Wall e ka kopanngoa ka mokhoa o sireletsehileng le meriana e meng. Leha ho le joalo, ke habohlokoa ho buisana le ngaka kapa setsebi sa meriana ho netefatsa hore ha ho na litšebelisano tse mpe le meriana e itseng. Hape ke habohlokoa ho latela litlhahiso tsa moetsi mabapi le nako le ho arohana le meriana e meng.

P: Ke mefuta efe e ka sehloohong ea Lactobacilli Cell Wall e sebelisoang ho li-supplement le lihlahisoa tsa probiotic?
A: Tse ling tsa mefuta e sebelisoang haholo ea Cell Wall Lactobacilli ke Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus acidophilus, le Lactobacillus casei. Mefuta ena e bontšitsoe hore e na le liphello tse molemo tsa bophelo bo botle 'me e ithutoa haholo mererong e fapaneng ea lipatlisiso tsa saense.

Qeto

Qetellong, Cell Wall Lactobacilli ke litloaelo tsa probiotic tse hlahelletseng ka matla a tsona a ho matlafatsa sesole sa 'mele le ho ntlafatsa bophelo bo botle ba mala. Sebopeho sa bona se ikhethang sa lerako la lisele se ba fa litšobotsi tse khethehileng, tse kang bokhoni ba ho khomarela mucosa ea mala le ho hanela maemo a mabe a pampiri ea mala.

Likokoana-hloko tsena tse molemo e 'nile ea e-ba taba ea liphuputso tse ngata tsa saense, tse tšehetsang katleho ea tsona ho thibela le ho phekola mafu a sa tšoaneng a mala, hammoho le ho laola tšoaetso le ho matlafatsa sesole sa' mele.

Patlisiso ho Cell Wall Lactobacilli e ntse e tsoela pele, ka sepheo sa ho utloisisa hamolemo mokhoa oa bona oa ho feto-fetoha ha sesole sa 'mele le tšebelisano ea bona le likokoana-hloko tse ling tse teng ka maleng. Ho feta moo, ho ntse ho hlahlojoa mahlale a macha ho ntlafatsa tlhahiso le botsitso ba li-probiotics tsena, ka hona ho netefatsa hore li sebetsa hantle le ho sebetsa hantle ha tsona.

Ka kakaretso, Lactobacilli Cell Wall e emela sesebelisoa se matla tšimong ea microbiota le bophelo bo botle ba mala. Karolo ea bona ea ho khothaletsa tekano e nepahetseng ea likokoana-hloko ka har'a pampitšana ea mala le bokhoni ba bona ba ho fetola sesole sa 'mele ho ba etsa khetho e tšepisang bakeng sa thibelo le kalafo ea maemo a fapaneng.