Khopolo ea YCell

Khopolo ea lisele ke tšiea ea bohlokoa thutong ea baeloji ea cellular Ho tloha ha e emoloa lekholong la bo17 la lilemo, khopolo ena e fetotse kutloisiso ea rona ea sebopeho le tšebetso ea lintho tse phelang, hammoho le lits'ebetso tse etsahalang ka har'a lisele. Sehloohong sena, re tla hlahloba khopolo ea lisele ka botlalo, ho tloha metheong ea eona ho isa lits'ebetso tsa eona lipatlisisong tsa morao-rao tsa biomedical. Re sebelisa mokhoa oa botekgeniki le molumo oa ho se nke lehlakore, re tla sekaseka melao-motheo ea khopolo ena le bohlokoa ba eona tsoelopeleng ea baeloji ea sejoale-joale.

Theory ea Cellular: Mokhoa oa Multidisciplinary oa Thuto ea Bophelo

Khopolo ea lisele ke "e 'ngoe ea metheo ea bohlokoa ka ho fetisisa thutong ea bophelo" le ho rarahana ha bona. E atameloa ho tsoa ponong ea li-multidisciplinary, khopolo ena e batla ho utloisisa lits'ebetso tsa baeloji boemong ba sele le kamano ea eona le tšebetso ea lefatše lohle ea libōpuoa tse phelang. Ho etsa sena, tsebo ea baeloji, k'hemistri, fisiks le makala a mang a mahlale a kopantsoe ho ⁢ sekaseka⁢ sebopeho, ts'ebetso le boitšoaro ba lisele.

Moko oa thuto ea ⁤cell ⁤ ke ho utloisisa hore lintho tsohle tse phelang li entsoe ka sele e le 'ngoe kapa ho feta, e leng likarolo tsa motheo tsa bophelo. Lisele tsena li na le litšobotsi tsa bohlokoa, tse kang matla a ho ikatisa, ho sebelisa matla, ho arabela linthong tse susumetsang le ho buisana. Ho feta moo, lisele tsohle li na le boitsebiso ba liphatsa tsa lefutso bo bolokiloeng liphatseng tsa tsona tsa lefutso, ebang ke DNA kapa RNA, e lekanyetsang litšobotsi tsa tsona le mesebetsi ea tsona.

Thutong ea theory ea lisele, ho bohlokoa ho utloisisa likarolo tse fapaneng tsa lisele le mesebetsi ea tsona e ikhethileng. Ka mohlala, lisele tsa lisele li arola le ho sireletsa lisele, li laola tsela eo lintho li kenang ka hare ho eona. Mokokotlo o boloka liphatsa tsa lefutso mme o laola mesebetsi ea lisele, ha li-organelles, tse kang mitochondria kapa chloroplasts, li etsa mesebetsi e khethehileng metabolism ea matla.

Melao-motheo ea Motheo ea Khopolo ea Lisele

Khopolo ea lisele ke e 'ngoe ea litšiea tsa motheo tsa baeloji ea kajeno. E theha melao-motheo e laolang sebōpeho le mosebetsi oa libōpuoa tsohle tse phelang. Ka mor'a moo, re tla hlahloba melao-motheo ea sehlooho ea khopolo ea lisele e fetotseng kutloisiso ea rona ea bophelo 'me e thehile metheo ea lipatlisiso tsa baeloji.

1. Sele e le karolo ea sebopeho⁢ le ts'ebetso: Ho ea ka khopolo ea sele, sele ke karolo ea motheo ea bophelo. Lintho tsohle tse phelang li entsoe ka lisele, ebang ke lisele tsa prokaryotic (tse se nang nucleus e hlalositsoeng) kapa lisele tsa eukaryotic (tse nang le nucleus e hlalositsoeng). Sele e 'ngoe le e 'ngoe e etsa mesebetsi ea bohlokoa 'me e etsa mehato e hlokahalang bakeng sa ho hlokomela le ho hlahisa bophelo.

2. Lefa la mehala: Khopolo ea lisele ⁢e thea⁤ hore sele e 'ngoe le e 'ngoe e tsoa ho sele e seng e ntse e le teng. Sena se bolela hore lisele lia arohana ho ikatisa le ho fetisa boitsebiso ba tsona ba lefutso ka meloko e latellanang. Ho ikatisa hona ha lisele ho bohlokoa bakeng sa khōlo le ntshetsopele ea lintho tse phelang, hammoho le ho lokisoa ha lisele le ho nchafatsa lisele tsa 'mele.

3. Cellular homeostasis: Lisele li boloka tikoloho ea ka hare e tsitsitseng le e leka-lekaneng ka mekhoa ea taolo. Sena se bolela bokhoni ba lisele ho laola khatello ea bona ea solute, ho laola pH ea bona, le ho boloka mocheso oa bona o sa feleng, har'a likarolo tse ling. Cellular homeostasis e bohlokoa bakeng sa tšebetso e nepahetseng ea lintho tse phelang 'me e tiisa tikoloho e loketseng bakeng sa karabelo ea lik'hemik'hale e hlokahalang bophelong.

Sebopeho le Mesebetsi ea Sele: Tlhahlobo e Felletseng

Tshekatshekong ena e qaqileng, re tla hlahloba sebopeho le mesebetsi ya motheo ya sele, e leng karolo ya motheo ya bophelo Sele ke sebopeho se rarahaneng, se hlophisitsweng haholo se etsang mesebetsi e fapaneng ya bohlokwa bakeng sa setshedi seo e leng ho sona. Ka tlhahlobo ena, re tla fumana hore na sebopeho sa sele se amana joang le mesebetsi ea sona.

Sele e entsoe ea likarolo tse 'maloa tsa bohlokoa tse sebetsang 'moho ho boloka tšebetso e nepahetseng ea' mele. Tsena li kenyelletsa:

– Plasma membrane: Ke lera le kantle la sele le pota-potileng le ho arola litaba tsa eona ho tikoloho e kantle. E sebetsa e le thibelo e khethollang, e lumellang ho kena ha lintho tse hlokahalang le ho thibela ho feta ha tse ka bang kotsi.

- Nucleus: Ke setsi sa taolo ea sele ⁢mme e na le ⁤ leseli la lefutso ka ⁤ mofuta oa DNA. Mona ke moo ho ngoloa le ho pheta-pheta ha liphatsa tsa lefutso, hammoho le tlhahiso ea lenģosa la RNA.

- Cytoplasm: Ke gelatinous matrix e fumanoang pakeng tsa lera la plasma le nucleus E na le li-organelles tse khethehileng tse etsang mesebetsi e itseng, tse kang motsoako oa liprotheine ho li-ribosomes le tlhahiso ea matla ho mitochondria.

Mesebetsi ea sele e bohlokoa ka ho lekana bakeng sa sebōpuoa. E meng ea mesebetsi ena e kenyelletsa tlhahiso ea matla ka ho phefumoloha ha lisele, motsoako oa liprotheine le lipalangoang, ho pheta-pheta le ho arohana ha lisele, le ho arabela ho tšusumetso e ka ntle. E 'ngoe le e' ngoe ea mesebetsi ena e bohlokoa bakeng sa ho boloka sebōpuoa le ho phela ha sona.

Ka bokhutšoanyane, sebopeho le mesebetsi ea sele ke lintho tse itšetlehileng ka tse ling hape li bohlokoa bakeng sa bophelo. Ka tlhahlobo e qaqileng ea sebōpeho sa tsona le mesebetsi ea tsona, re ka utloisisa hamolemo kamoo lisele li sebetsang kateng ho boloka tšebetso ea lintho tse phelang. Sele ke sebopeho se hlollang le se rarahaneng, ’me boithuto ba eona bo re thusa ho hlahloba liphiri tsa bophelo ka bobona.

Likarolo tsa Bohlokoa tsa Cell le litšebelisano tsa tsona

Sele ke karolo ea motheo ea bophelo 'me e entsoe ka likarolo tse sa tšoaneng tsa bohlokoa tse sebetsang hammoho ho netefatsa hore e sebetsa hantle. Likarolo tsena li kenyelletsa:

• Lera la plasma: Ke lera le tšesaane le pota-potileng le ho sireletsa sele, ho lumella ho feta ha lintho tse itseng.
• Saitoplasm: Ke gelatinous matrix moo mesebetsi e mengata ea cellular e etsoang. Mona ke li-organelle tsa cellular, tse kang ribosomes, mitochondria, le endoplasmic reticulum, har'a tse ling.
• Sehlohlolo: Ke setsi sa taolo ea sele, se na le thepa ea liphatsa tsa lefutso (DNA) 'me e pota-potiloe ke lera le habeli le bitsoang enfelopo ea nyutlelie.

Likarolo tsena li sebelisana ka mekhoa ea biochemical le ea 'mele ho netefatsa homeostasis le tlhokomelo ea sele. Ka mohlala, lera la plasma le laola ho tsamaisoa ha lintho ho kena le ho tsoa ka seleng, ho lumella ho kena ha limatlafatsi le ho felisa litšila. Cytoplasm e na le li-organelle tsa cellular, tse ikarabellang bakeng sa ho etsa mesebetsi e itseng, joalo ka protheine synthesis ho ribosomes kapa tlhahiso ea matla ho mitochondria. Nucleus e laola ho ikatisa ha DNA, ho ngoloa ha protheine le phetolelo, 'me e phetha karolo ea bohlokoa ho nts'etsopele ea lisele le ho khetholla.

Ka bokhutšoanyane, likarolo tsa bohlokoa tsa sele li sebetsa ka tšebelisano e haufi ho netefatsa ho phela le ho sebetsa ha microcosm ena ea tlhaho. Tlhophiso e nepahetseng ea eona le ho leka-lekana ke tsa bohlokoa ho boloka botšepehi ba sele le ho netefatsa ho phela ha lintho tse phelang.

Likhopolo Tse Fapaneng Tsa Lisele le Khopolo ea Tsona ea Tsona ho Nalane le Nalane

Khopolo ea lisele, e leng o mong oa metheo ea baeloji ea sejoale-joale, e tsoetse pele ea nalane ha tsebo le mahlale a macha a ile a sibolloa Ka tlase re hlahisa tse ling tsa likhopolo tse fapaneng tsa lisele le tlatsetso ea tsona ea bohlokoa ntlafatsong ea kutloisiso ea rona ea sebopeho le tšebetso ea lisele.

1. Khopolo ea moloko o itlelang feela: Khopolo ena, eo hape e tsejoang e le abiogenesis, e ne e amoheloa hohle mehleng ea boholo-holo Ho ne ho lumeloa hore lisele li ka itlhahela feela linthong tse sa pheleng, tse kang seretse kapa nama e bolang. Leha ho le joalo, ha saense e ntse e tsoela pele, liteko tsa Louis Pasteur le bo-rasaense ba bang li ile tsa bontša ka ho hlaka hore lintho tsohle tse phelang li tsoa linthong tse ling tse neng li le teng pele.

2. Khopolo ea sele e le 'ngoe: Lekholong la bo17 la lilemo, Anton van Leeuwenhoek, a sebelisa ka lekhetlo la pele microscope, e ile ea sibolla hore lisele e ne e le likarolo tsa motheo tsa lintho tse phelang. Khopolo ena e fana ka maikutlo a hore lintho tse phelang li entsoe ka sele e le 'ngoe, tse kang protozoa le baktheria. Se fumanoeng sena se ralile motheo oa kutloisiso e kholoanyane ea⁣ mefuta-futa ea lisele le ho hlaha ha khopolo ea kajeno ea lisele.

3. Khopolo ea kajeno ea lisele: Khopolo ena, e qapiloeng bohareng ba lekholo la bo19 la lilemo ke Matthias Schleiden le Theodor Schwann, e tiisa hore libōpuoa tsohle tse phelang li entsoe ka sele e le ’ngoe kapa ho feta. Ho feta moo, e bolela hore lisele ke likarolo tsa motheo tsa sebopeho le ts'ebetso ea lintho tse phelang, khopolo ea kajeno ea lisele e boetse e fana ka maikutlo a hore mesebetsi eohle ea bohlokoa, e kang ho ikatisa, ho hōla, le metabolism, e etsahala ka har'a lisele. Khopolo ena e amoheloa ke batho ba bangata ’me e ntse e le motheo oa tsebo ea rōna ea ha joale ea baeloji ea lisele.

Bohlokoa ba Lipatlisiso ho Theory ea Cellular ho Ntšetsa Pele Tsebo ea Saense

Patlisiso ho theory ea lisele e na le karolo ea bohlokoa tsoelopeleng ea tsebo ea mahlale. Khopolo ea lisele ke motheo oa baeloji ea morao-rao ’me e re lumella ho utloisisa hore na lintho tse phelang li sebetsa joang boemong ba microscopic. Ka lipatlisiso sebakeng sena, bo-ramahlale ba ka sibolla lits'ebetso tse ncha tsa cellular, ba utloisisa mafu hantle, 'me ba etsa liphekolo tse ncha.

E 'ngoe ea lintlha tsa bohlokoa tsa lipatlisiso tsa theory ea lisele ke thuto ea sebopeho le tšebetso ea lisele. Lisele ke likarolo tsa motheo tsa lintho tse phelang, 'me lipatlisiso tsena li re thusa ho utloisisa hore na li hlophisitsoe joang le hore na li sebelisana joang. Ba sebelisa mekhoa e tsoetseng pele e kang fluorescence microscopy le flow cytometry, bo-rasaense ba khona ho bona lisele li sebetsa le ho ithuta likarolo tsa tsona tse fapaneng, tse kang nucleus, cytoplasm le organelles.

Karolo e 'ngoe ea bohlokoa ea lipatlisiso tsa khopolo ea lisele ke thuto ea karohano ea lisele le ho ikatisa. Ho utloisisa hore na lisele li arola le ho ikatisa joang ho bohlokoa ho utloisisa nts'etsopele ea lintho tse phelang le hore na lisele tse senyehileng li lokisoa joang. Ho feta moo, thuto ea karohano ea lisele e bohlokoa lipatlisisong tsa mofetše, kaha mefuta e mengata ea mofetše e amana le ho se sebetse hantle ha mofetše. ts'ebetso ena.

Lits'ebeliso tsa Khopolo ea Mehala ho Nts'etsopele ea Liphekolo tse Hlahang tsa Meriana

Likopo tsa Khopolo ea Lisele ho Tsoelopele ea Kalafo e Ncha ea Bongaka

Theory Cellular e fetotse lefapha la bongaka ’me e bile ea bohlokoa ntlafatsong ea mekhoa e mecha ea phekolo ea meriana. Ka lebaka la khopolo ena, bo-rasaense ba khonne ho utloisisa ka botlalo ho sebetsa ha lisele le karolo ea tsona 'meleng oa motho. Sena se lebisitse ho thehoeng ha liphekolo le meriana e sebetsang haholoanyane le e tobileng, e fanang ka tšepo ho bakuli ba nang le mafu a tebileng.

Tse ling tsa ts'ebeliso ea mantlha ea Cell Theory ho nts'etsopele ea mekhoa e mecha ea kalafo e kenyelletsa:

• Kalafo ea mehala: Kalafo ea lisele e thehiloe tšebelisong ea lisele tse phetseng hantle ho nka sebaka kapa ho lokisa lisele tse senyehileng. Ka lebaka la Cellular Theory, bo-rasaense ba khonne ho tseba le ho khetha lisele tse loketseng ka ho fetisisa bakeng sa mofuta o mong le o mong oa phekolo, joalo ka lisele tsa stem.
• Boenjineri ba Tishu: Theory ea Cellular e lumeletse tsoelo-pele ho thehoeng ha lisele le litho tsa maiketsetso tse sebelisang lisele tse phelang. Mokhoa ona oa phetoho o butse monyetla oa liphekolo tsa motho ka mong le ⁢ monyetla oa ho nchafatsa lisele tse senyehileng.
• Phekolo ea liphatsa tsa lefutso: Theory Cell e bile ea bohlokoa ntlafatsong ea phekolo Phekolo ea liphatsa tsa lefutso, e kenyelletsang ho kenya liphatsa tsa lefutso tse phetseng hantle liseleng tsa mokuli ho lokisa ho se tloaelehe ha liphatsa tsa lefutso. Mokhoa ona o tšepisang o na le monyetla oa ho phekola mafu a lefutso le lefutso.

Ka bokhutšoanyane, Theory ea Cellular e fetiselitse meriana libakeng tse ncha, e nolofalletsang nts'etsopele ea mekhoa e mecha ea phekolo ea meriana le ho fana ka tšepo ho bakuli ba nang le maemo a bongaka a thata ho a phekola. Ka lebaka la kutloisiso e ntseng e eketseha ea lisele le tsela eo li sebetsang ka eona, tsoelo-pele ea saense sebakeng sena e tšepisa ho ntlafatsa ⁤ boleng ba bophelo ba batho ba bangata nakong e tlang.

Litlhahiso bakeng sa Tšebeliso e Nepahetseng ea Khopolo ea Cellular ho Patlisiso ea Motheo le e Sebelisitsoeng

Khopolo ea lisele e bohlokoa liphuputsong tse peli tsa motheo le tse sebelisoang lefapheng la baeloji. Ka tlase ho na le likhothaletso tsa ho netefatsa tšebeliso e nepahetseng ea khopolo ena lithutong tsa mahlale.

1. Sebelisa maekerosekoupo tsa boleng bo holimo: E le ho hlokomela le ho hlahloba lisele ka nepo, li-microscopes li bohlokoa. boleng bo phahameng tse fanang ka tharollo e lekaneng. Sena se tla lumella ho bona ka botlalo likarolo tsa cellular le ho li etsa tlhahlobo e felletseng ea tsona.

2.⁤ Etsa mekhoa ea ho silafatsa: Mekhoa ea ho silafatsa ke lisebelisoa tsa bohlokoa tsa ho totobatsa likarolo tse fapaneng tsa cellular le ho thusa pono ea tsona. Tšebeliso ea lidae tse khethehileng e thusa ho khetholla likarolo tse fapaneng tsa sele, joalo ka nucleus, lera la plasma kapa li-organelles tse ka hare. Mekhoa ena e lumella tlhahlobo e ntle ea lisele le ho thusa ho fumana liphetho tse nepahetseng haholoanyane.

3. Boloka maemo a nepahetseng a ho hola: Ho bohlokoa ho fana ka lisele ka tikoloho e lekaneng bakeng sa kholo le nts'etsopele ea tsona. Sena se kenyelletsa ho boloka maemo a nepahetseng a ho hola, joalo ka mocheso o nepahetseng, mongobo le pH. Ho feta moo,⁤ ho bohlokoa ho fa lisele limatlafatsi tse hlokahalang bakeng sa ho sebetsa hantle.

Lipotso le Likarabo

P: Theory ⁢cell ke eng?
K: Khopolo ea lisele ke molao-motheo oa motheo thutong ea baeloji o bolelang hore lintho tsohle tse phelang li entsoe ka sele e le ’ngoe kapa ho feta, le hore lisele tsena ke karolo ea motheo ea bophelo.

P: Ke lintlha life tse ka sehloohong tsa khopolo ea lisele?
A: Lintlha tse ka sehloohong tsa khopolo ea lisele ke: 1) Libōpuoa tsohle tse phelang li entsoe ka sele e le 'ngoe kapa ho feta; 2) Sele ke karolo ea sebopeho le tšebetso ea lintho tsohle tse phelang; 3) Lisele tsohle li tsoa liseleng tse ling tse seng li ntse li le teng.

P: Khopolo ea lisele e ile ea hlahisoa neng?
K: Khopolo ea lisele e ile ea hlahisoa lekholong la 1830th, haholo-holo ke bo-rasaense Matthias Schleiden le Theodor Schwann, lilemong tsa bo-XNUMX.

P: Bohlokoa ba khopolo ea lisele ho baeloji ea sejoale-joale ke bofe?
K: Khopolo ea lisele e bohlokoa haholo thutong ea sejoale-joale ea baeloji, kaha e fana ka moralo oa mohopolo bakeng sa ho utloisisa sebopeho le tšebetso ea lintho tse phelang. ⁤Ho phaella moo, e re lumella ho utloisisa mekhoa ea motheo ea lisele, tse kang karohano ea lisele, metabolism le lefutso.

P: Tsoelopele ea mahlale e amanang le thuto ea lisele ke efe?
K: Tsoelopele ea mahlale e amanang le khopolo ea lisele e mengata. E 'ngoe ea tse hlokomelehang ⁤ke nts'etsopele ea ⁣microscopy, e entseng hore ho khonehe ho bona lisele ⁤ ka botlalo. Ho feta moo,⁢ lithuto tsa liphatsa tsa lefutso le baeloji ea limolek'hule li fane ka kutloisiso e tebileng ea lits'ebetso tsa cellular le lefa.

P: Khopolo ea lisele e na le litlamorao life? bongaka?
K: Khopolo ea lisele ke ea bohlokoa ho tsa bongaka, kaha⁤ e re lumella ho utloisisa ⁢mafu ka⁤ mabapi le ho se sebetse hantle ha lisele. Mafu a mangata, a kang mofetše, a bakoa ke ho fetoha ha tšebetso ea lisele. Ho phaella moo, tsoelo-pele ea phekolo ea lisele le meriana e nchafatsang e thehiloe kutloisisong ea melao-motheo ea khopolo ea lisele.

P: Na ho na le mekhelo thutong ea lisele?
A: Hajoale, ha ho mokhelo ho theory ea lisele tse fumanoeng. Lintho tsohle tse phelang tse ithutoang ho fihlela joale li entsoe ka sele e le 'ngoe kapa ho feta. Leha ho le joalo, lipatlisiso tsa saense li ntse li tsoela pele 'me kamehla ho na le monyetla oa ho sibolla liketsahalo tsa potso eo kapa ho atolosa tsebo ea rona ea hona joale.

P: Na ho na le kamano pakeng tsa khopolo ea lisele le lithuto tse ling tsa mahlale?
K: E, khopolo ea lisele e na le maqhama le likarolo tse ling tsa saense. Baeloji ea limolek'hule, liphatsa tsa lefutso, physiology le histology ke tse ling tsa lithuto tse amanang haufi-ufi le khopolo ea lisele. Ho feta moo, khopolo ea lisele e boetse e na le ts'ebeliso le litlamorao mafapheng a joalo ka bongaka, biotechnology, le lipatlisiso mabapi le nts'etsopele ea lithethefatsi tse ncha.

P: Ho na le bohlokoa bofe ba khopolo ea lisele ho tsoelo-pele ea morao-rao ea theknoloji?
K: Khopolo ea lisele e amana le tsoelopele ea morao-rao ea theknoloji, kaha e lumelletse nts'etsopele ea mekhoa e joalo ka boenjineri ba lithane, cloning le phetoho ea liphatsa tsa lefutso. Ho feta moo, ho utloisisa lits'ebetso tsa mantlha tsa cellular⁢ ho bohlokoa moralong le nts'etsopele ea litlhare le liphekolo tse ncha.

Maikutlo a ho Qetela

Ka bokhutšoanyane, khopolo ea lisele e bile motheo oa motheo o lumelletseng tsoelo-pele le kutloisiso ea baeloji ea lisele ho theosa le lilemo. Ho tloha qalong ea eona ka se hlokometsoeng ke Robert Hooke, ho ea liphuputsong tsa morao-rao tsa baeloji ea limolek’hule, khopolo ena e fane ka sebōpeho se tiileng le se nang le maikutlo a ho utloisisa tlhophiso le tšebetso ea libōpuoa tse phelang.

Ka mohopolo oa sele e le karolo ea mantlha ea bophelo, khopolo ena e re lumelletse ho hlahloba le ho sibolla mekhoa ea mantlha ea ts'ebetso ea baeloji, ho tloha ho ikatisa ha DNA ho isa ho thehoeng ha lisele le litho. Ho feta moo, khopolo ea lisele e lebisitse tsoelopeleng ea biotechnology le meriana, ka ho fana ka lisebelisoa tsa ho utloisisa le ho phekola maloetse. boemong ba sele.

Leha ho le joalo, ho sa tsotellehe katleho e fumanoeng ka lebaka la khopolo ena, ho ntse ho e-na le lintho tse ngata tse sa tsejoeng tse lokelang ho senoloa lefapheng la baeloji ea lisele. Likhatelo-pele tsa morao-rao tsa theknoloji, tse kang microscope ea boemo bo phahameng le mekhoa ea tatellano ea DNA, li fana ka menyetla e mecha ea ho phenya ka botebo boithutong ba lisele le tšebetso ea tsona, hammoho le ho hlahloba tšebelisano pakeng tsa lisele tse fapaneng ⁤ ntho e phelang.

Ka bokhutšoane, khopolo ea lisele e bile sesebelisoa sa bohlokoahali sa ho utloisisa baeloji maemong a manyenyane ebile e ntse e tsoela pele. Ha kutloisiso ea rona ea lisele le tsela eo li sebetsang ka eona e ntse e hola, tsebo ea rona ea lefats'e ka kakaretso ea baeloji ea eketseha. Khopolo ea lisele e lulang e fetoha e tla tsoela pele ho tataisa lipatlisiso le ho sibolloa lefatšeng le tsotehang la baeloji ea lisele.