Umahluko phakathi kwe-chondroblasts kunye ne-chondrocytes

Uhlaziyo lokugqibela: 26/04/2023
Umbhali: USebastian Vidal

Intshayelelo

I-Cartilage sisihlunu esikhethekileyo esidibanisayo esinomsebenzi obalulekileyo emzimbeni wethu njengoko isebenza njenge-absorber yokothuka kumalungu kwaye inceda ukubumba izakhiwo zethu zomzimba. I-Chondroblasts kunye ne-chondrocytes ziiseli ezikhethekileyo ezifumaneka kwi-cartilage kwaye zidlala indima ebalulekileyo ekubunjweni nasekugcinweni kwayo.

Yintoni i-chondroblasts?

I chondroblasts Ziiseli ezincinci ezifumaneka kwi-cartilage ekhulayo. Banoxanduva lokuvelisa kunye nokufihla ubuninzi be-matrix ye-extracellular, eyona nto iqulethwe yi-collagen kunye ne-proteoglycans. Xa i-matrix ye-extracellular iveliswa, i-chondroblasts ibanjwe kuyo kwaye ibe yi-chondrocytes.

Ziziphi iichondrocytes?

I iichondrocytes Ziiseli ezikhulileyo ezifumaneka kwi-cartilage yabantu abadala. Ngokungafani ne-chondroblasts, i-chondrocytes ayihlukanisi kwaye inomsebenzi omncinci. Umsebenzi wayo oyintloko kukugcina i-matrix ye-extracellular eyenziwa yi-chondroblasts kwaye iqinisekise ukuba izicubu zifakwe kakuhle. I-Chondrocytes inokuphila amashumi eminyaka, kodwa njengoko sikhula, ukukwazi kwabo ukugcina i-matrix engaphandle kwe-extracellular kuyancipha kwaye oku kunokukhokelela kwizifo ezifana ne-osteoarthritis.

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Nguwuphi umahluko phakathi kwe-chondroblasts kunye ne-chondrocytes?

  • I-Chondroblasts iiseli ezincinci ezifumaneka kwi-cartilage ekhulayo, ngelixa i-chondrocytes iiseli ezivuthiweyo ezifumaneka kwi-cartilage yabantu abadala.
  • I-Chondroblasts inoxanduva lokuvelisa kunye nokukhuselwa kwe-matrix ye-extracellular, ngelixa i-chondrocytes inoxanduva lokugcina i-matrix ye-extracellular.
  • I-Chondroblasts ibe yi-chondrocytes emva kokuba ibanjwe kwi-matrix ye-extracellular, ngelixa i-chondrocytes ayinakho ukukwazi ukwahlula.

Izigqibo

Isishwankathelo, i-chondroblasts kunye ne-chondrocytes ziiseli ezikhethekileyo ezenza imisebenzi eyahlukeneyo kwi-cartilage. I-Chondroblasts inoxanduva lokuvelisa i-matrix ye-extracellular, ngelixa i-chondrocytes inomsebenzi wokuyigcina. Kubalulekile ukuqonda umahluko phakathi kwezi seli ukuqonda ukubunjwa kunye nokugcinwa kwe-cartilage emzimbeni wethu.